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In enzymology, an aminodeoxychorismate synthase ((EC 2.6.1.85 )) is an enzyme that catalyzes the chemical reaction :chorismate + L-glutamine 4-amino-4-deoxychorismate + L-glutamate Thus, the two substrates of this enzyme are chorismate and L-glutamine, whereas its two products are 4-amino-4-deoxychorismate and L-glutamate. It is part of a pathway for the biosynthesis of ''para''-aminobenzoic acid (PABA); a precursor for the production of folates. Folates are family of cofactors that are essential for living organisms. Folate cofactors are used in several one-carbon transfer reactions required during the synthesis of essential metabolites, including methionine and thymidylate.〔 Aminodeoxychorsimate synthase (PabB), a 51 kDa protein in ''E. coli'', is encoded by the gene ''pabB''.〔 4-amino-4-deoxychorismate, the product of PabB, can be converted to ''para''-aminobenzoic acid by the enzyme 4-amino-4-deoxychorismate lyase (PabC). == Nonmenclature == This enzyme belongs to the class of transferases. This means that aminodeoxychorismate synthase catalyzes the transfer of one functional group from a molecule to another. Specifically, aminodeoxychorismate synthase is a transaminase that transfers an amino group to a keto acid. The systematic name is Chorismate:L-glutamine aminotransferase. Formerly aminodeoxychorismate synthase was referred to as PABA synthase; however this name is no longer recommended as it is understood that the formation of PABA requires the action of a further enzyme (4-amino-4-deoxychorismate lyase). Common names that the enzyme goes by are: * Aminodeoxychorismate synthase * ADC synthase * 4-amino-4-deoxychorismate synthase * PabB 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Aminodeoxychorismate synthase」の詳細全文を読む スポンサード リンク
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